Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na(+)‐Taurocholate Cotransporting Polypeptide

Cholestasis‐induced accumulation of bile acids in the liver leads to farnesoid X receptor (FXR)‐mediated transcriptional down‐regulation of the bile acid importer Na(+)‐taurocholate cotransporting protein (NTCP) and to induction of endoplasmic reticulum (ER) stress. However, whether ER stress affect...

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Detalles Bibliográficos
Autores principales: Robin, Marion J.D., Appelman, Monique D., Vos, Harmjan R., van Es, Robert M., Paton, James C., Paton, Adrienne W., Burgering, Boudewijn, Fickert, Peter, Heijmans, Jarom, van de Graaf, Stan F.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287483/
https://www.ncbi.nlm.nih.gov/pubmed/30556041
http://dx.doi.org/10.1002/hep4.1262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287483/
https://www.ncbi.nlm.nih.gov/pubmed/30556041
http://dx.doi.org/10.1002/hep4.1262

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