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Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated‐Beta‐Catenin Signaling in Murine Liver and Human Liver Cancer Cells

Prohibitin1 (PHB1) is a mitochondrial chaperone with diverse functions that include cell proliferation, apoptosis, and mitochondrial homoeostasis. Liver‐specific Phb1 knockout (KO) mice develop spontaneous injury and hepatocellular carcinoma (HCC). Our previous work demonstrated that PHB1 negatively...

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Detalles Bibliográficos
Autores principales: Mavila, Nirmala, Tang, Yuanyuan, Berlind, Joshua, Ramani, Komal, Wang, Jiaohong, Mato, José M., Lu, Shelly C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287485/
https://www.ncbi.nlm.nih.gov/pubmed/30556043
http://dx.doi.org/10.1002/hep4.1257