Cargando…

Prohibitin 1 Acts As a Negative Regulator of Wingless/Integrated‐Beta‐Catenin Signaling in Murine Liver and Human Liver Cancer Cells

Prohibitin1 (PHB1) is a mitochondrial chaperone with diverse functions that include cell proliferation, apoptosis, and mitochondrial homoeostasis. Liver‐specific Phb1 knockout (KO) mice develop spontaneous injury and hepatocellular carcinoma (HCC). Our previous work demonstrated that PHB1 negatively...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mavila, Nirmala, Tang, Yuanyuan, Berlind, Joshua, Ramani, Komal, Wang, Jiaohong, Mato, José M., Lu, Shelly C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287485/ https://www.ncbi.nlm.nih.gov/pubmed/30556043 http://dx.doi.org/10.1002/hep4.1257

Ejemplares similares

Inhibition of CREB binding protein-beta-catenin signaling down regulates CD133 expression and activates PP2A-PTEN signaling in tumor initiating liver cancer cells
por: Tang, Yuanyuan, et al.
Publicado: (2018)

Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models
por: Ramani, Komal, et al.
Publicado: (2022)

Correction: Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models
por: Ramani, Komal, et al.
Publicado: (2023)

The Emerging Roles of Cancer Stem Cells and Wnt/Beta-Catenin Signaling in Hepatoblastoma
por: Mavila, Nirmala, et al.
Publicado: (2019)

Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease
por: Barbier-Torres, Lucía, et al.
Publicado: (2022)

Wingless/It/β-catenin signaling in liver metastasis from colorectal cancer: A focus on biological mechanisms and therapeutic opportunities
por: Selvaggi, Federico, et al.
Publicado: (2023)

Deletion of adipocyte prohibitin 1 exacerbates high‐fat diet‐induced steatosis but not liver inflammation and fibrosis
por: Wang, Xiaolin, et al.
Publicado: (2022)

Wingless and the argosomes
por: Wells, William A.
Publicado: (2001)

β-catenin induces expression of prohibitin gene in acute leukemic cells
por: Kim, Dong Min, et al.
Publicado: (2017)

Methionine adenosyltransferase α2 sumoylation positively regulate Bcl-2 expression in human colon and liver cancer cells
por: Tomasi, Maria Lauda, et al.
Publicado: (2015)

Prominin-1 promotes restitution of the murine extrahepatic biliary luminal epithelium following cholestatic liver injury
por: Zhong, Allen, et al.
Publicado: (2023)

Functional Human and Murine Tissue‐Engineered Liver Is Generated from Adult Stem/Progenitor Cells
por: Mavila, Nirmala, et al.
Publicado: (2016)

Prohibitin Expression Is Decreased in the Regenerating Liver but Not in Chemically Induced Hepatic Tumors in Rats
por: Tanno, Satoshi, et al.
Publicado: (1997)

Protection of Armadillo/β-Catenin by Armless, a Novel Positive Regulator of Wingless Signaling
por: Reim, Gerlinde, et al.
Publicado: (2014)

A Wingless Flight
por: Yu, Xiang
Publicado: (2003)

Role of Methionine Adenosyltransferase Genes in Hepatocarcinogenesis
por: Ramani, Komal, et al.
Publicado: (2011)

Inhibitors of endocytosis prevent Wnt/Wingless signalling by reducing the level of basal β-catenin/Armadillo
por: Gagliardi, Maria, et al.
Publicado: (2014)

Nuclear partitioning of Prohibitin 1 inhibits Wnt/β-catenin-dependent intestinal tumorigenesis
por: Alula, Kibrom M., et al.
Publicado: (2020)

An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling
Publicado: (1996)

Fibroblast Growth Factor Receptor-Mediated Activation of AKT-β-Catenin-CBP Pathway Regulates Survival and Proliferation of Murine Hepatoblasts and Hepatic Tumor Initiating Stem Cells
por: Mavila, Nirmala, et al.
Publicado: (2012)

Carrier of Wingless (Cow), a Secreted Heparan Sulfate Proteoglycan, Promotes Extracellular Transport of Wingless
por: Chang, Yung-Heng, et al.
Publicado: (2014)

Prohibitin-1 Transgenic Mice Revealed an Important Role of Prohibitin in Testicular Steroidogenesis
por: Bassi, Geetika, et al.
Publicado: (2021)

Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors
por: Schweizer, Liang, et al.
Publicado: (2003)

Investigation of grape sap on wingless/integrated and β-catenin genes expression with histological factors on the hair follicle in rat
por: Kazemi, Mohammad, et al.
Publicado: (2020)

RNA-Seq Reveals Different Gene Expression in Liver-Specific Prohibitin 1 Knock-Out Mice
por: Lee, Kyuwon, et al.
Publicado: (2021)

Prohibitins in neurodegeneration and mitochondrial homeostasis
por: Fernandez-Abascal, Jesus, et al.
Publicado: (2022)

Expression of hepatocyte nuclear factor 4 alpha, wingless-related integration site, and β-catenin in clinical gastric cancer
por: Hu, Qian, et al.
Publicado: (2022)

A sharp end to sugary Wingless travels
por: Droujinine, Ilia A., et al.
Publicado: (2014)

Powerful Drosophila screens that paved the wingless pathway
por: Jenny, Fabian Heinz, et al.
Publicado: (2015)

Probing the canonicity of the Wnt/Wingless signaling pathway
por: Franz, Alexandra, et al.
Publicado: (2017)

Extracellular spreading of Wingless is required for Drosophila oogenesis
por: Wang, Xiaoxi, et al.
Publicado: (2021)

Opposing function of mitochondrial prohibitin in aging
por: Artal-Sanz, Marta, et al.
Publicado: (2010)

The Prohibitins: emerging roles in diverse functions
por: Mishra, Suresh, et al.
Publicado: (2006)

The function of prohibitins in mitochondria and the clinical potentials
por: Oyang, Linda, et al.
Publicado: (2022)

CaMK IV phosphorylates prohibitin 2 and regulates prohibitin 2-mediated repression of MEF2 transcription
por: Sun, Luguo, et al.
Publicado: (2011)

Lipopolysaccharide-induced innate immune responses are exacerbated by Prohibitin 1 deficiency and mitigated by S-adenosylmethionine in murine macrophages
por: Jung, Soohan, et al.
Publicado: (2020)

Activation of WNT/Beta‐Catenin Signaling and Regulation of the Farnesoid X Receptor/Beta‐Catenin Complex After Murine Bile Duct Ligation
por: Zhang, Rong, et al.
Publicado: (2019)

Methionine adenosyltransferases in liver cancer
por: Murray, Ben, et al.
Publicado: (2019)

MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1
por: Cirilo, Priscila Daniele Ramos, et al.
Publicado: (2017)

Kinesin family member 3A induces related diseases via wingless-related integration site/β-catenin signaling pathway
por: Liu, Shupeng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8hpujn94molbhfquv399e09gv8