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Triplet CFTR modulators: future prospects for treatment of cystic fibrosis

Cystic fibrosis (CF) is an autosomal recessive genetic disease characterized by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is a chloride channel responsible for ion flow across epithelial surfaces of lung, sinuses, pancreas, intestine, and liver. Researchers ha...

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Detalles Bibliográficos
Autor principal:	Chaudary, Nauman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287538/ https://www.ncbi.nlm.nih.gov/pubmed/30584312 http://dx.doi.org/10.2147/TCRM.S147164

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