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Stability, safety, and transcorneal mechanistic studies of ophthalmic lyophilized cyclosporine-loaded polymeric micelles
INTRODUCTION: Cyclosporine-A (CsA) is generally used as an immunosuppressant and is also prescribed for some ophthalmic applications such as vernal keratoconjunctivitis and dry eye. However, it is limited clinically due to its low aqueous solubility and ocular bioavailability. METHODS: In this work,...
Autores principales: | Shen, Yan, Yu, Yinglan, Chaurasiya, Birendra, Li, Xiaolian, Xu, Ying, Webster, Thomas J, Tu, Jiasheng, Sun, Runing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287540/ https://www.ncbi.nlm.nih.gov/pubmed/30584300 http://dx.doi.org/10.2147/IJN.S173691 |
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