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Anthelmintic drug actions in resistant and susceptible C. elegans revealed by electrophysiological recordings in a multichannel microfluidic device

Many anthelmintic drugs used to treat parasitic nematode infections target proteins that regulate electrical activity of neurons and muscles: ion channels (ICs) and neurotransmitter receptors (NTRs). Perturbation of IC/NTR function disrupts worm behavior and can lead to paralysis, starvation, immune...

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Detalles Bibliográficos
Autores principales:	Weeks, Janis C., Robinson, Kristin J., Lockery, Shawn R., Roberts, William M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Articles from the scientific meeting: "Anthelmintics: From Discovery to Resistance III", pp. 494 - 628.
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287544/ https://www.ncbi.nlm.nih.gov/pubmed/30503202 http://dx.doi.org/10.1016/j.ijpddr.2018.10.003

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