Cargando…

MicroRNA 486-3p directly targets BIK and regulates apoptosis and invasion in colorectal cancer cells

BACKGROUND: MicroRNAs influence almost every genetic pathway and are involved in colorectal cancer (CRC). However, the biological role of miR486-3p in CRC remains to be elucidated. METHODS: In this study, miR486-3p expression in CRC cell lines and normal colonic epithelial cells was determined. Afte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Li, Jing, Li, Han, Jing, Wang, Guiying, Liu, Yan, Zhang, Xue, Wang, Yudong, Wang, Feifei, Ma, Hongqing, Liu, Yibing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287550/ https://www.ncbi.nlm.nih.gov/pubmed/30584337 http://dx.doi.org/10.2147/OTT.S180354

Ejemplares similares

MicroRNA-486-5p and microRNA-486-3p: Multifaceted pleiotropic mediators in oncological and non-oncological conditions
por: ElKhouly, Aisha M., et al.
Publicado: (2020)

Circulating MicroRNA-486 and MicroRNA-146a serve as potential biomarkers of sarcopenia in the older adults
por: Liu, Huang-Chun, et al.
Publicado: (2021)

MicroRNA-145 and microRNA-486 are potential serum biomarkers for vascular calcification
por: Fernández-Villabrille, Sara, et al.
Publicado: (2023)

Periplocymarin Induced Colorectal Cancer Cells Apoptosis Via Impairing PI3K/AKT Pathway
por: Cheng, Yi, et al.
Publicado: (2021)

Transcription factor FoxO1, the dominant mediator of muscle wasting in chronic kidney disease, is inhibited by microRNA-486
por: Xu, Jing, et al.
Publicado: (2012)

Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis
por: Gillissen, Bernhard, et al.
Publicado: (2007)

MicroRNAs and Apoptosis in Colorectal Cancer
por: Wang, Hsiuying
Publicado: (2020)

Propofol inhibits lung cancer cell viability and induces cell apoptosis by upregulating microRNA-486 expression
por: Yang, N., et al.
Publicado: (2017)

MicroRNA-486 as a Biomarker for Early Diagnosis and Recurrence of Non-Small Cell Lung Cancer
por: Li, Wanshuai, et al.
Publicado: (2015)

The Anti-fibrotic Effects and Mechanisms of MicroRNA-486-5p in Pulmonary Fibrosis
por: Ji, Xiaoming, et al.
Publicado: (2015)

Regulatory roles of microRNA-708 and microRNA-31 in proliferation, apoptosis and invasion of colorectal cancer cells
por: LEI, SAN-LIN, et al.
Publicado: (2014)

Correction: MicroRNA-486 as a Biomarker for Early Diagnosis and Recurrence of Non-Small Cell Lung Cancer
por: Li, Wanshuai, et al.
Publicado: (2016)

MicroRNA-486-5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression
por: Shi, Yingying, et al.
Publicado: (2019)

MicroRNA-486-5p Suppresses Lung Cancer via Downregulating mTOR Signaling In Vitro and In Vivo
por: Ding, Lei, et al.
Publicado: (2021)

MicroRNA 486-3P as a stability marker in acute coronary syndrome
por: Wei, Tianling, et al.
Publicado: (2016)

MicroRNA-511 Inhibits Cellular Proliferation and Invasion in Colorectal Cancer by Directly Targeting Hepatoma-Derived Growth Factor
por: He, Saifei, et al.
Publicado: (2018)

Long non-coding RNA TUG1 knockdown prevents neurons from death to alleviate acute spinal cord injury via the microRNA-338/BIK axis
por: Wu, Hongbo, et al.
Publicado: (2021)

Ligand-induced BIK1 monoubiquitination regulates plant immunity
por: Ma, Xiyu, et al.
Publicado: (2020)

Circ_0005320 promotes oral squamous cell carcinoma tumorigenesis by sponging microRNA-486-3p and microRNA-637
por: Zheng, Xiaotao, et al.
Publicado: (2021)

BIK1 and ERECTA Play Opposing Roles in Both Leaf and Inflorescence Development in Arabidopsis
por: Chen, Sufen, et al.
Publicado: (2019)

MicroRNA-486-3p Regulates γ-Globin Expression in Human Erythroid Cells by Directly Modulating BCL11A
por: Lulli, Valentina, et al.
Publicado: (2013)

MicroRNA-486-3p functions as a tumor suppressor in oral cancer by targeting DDR1
por: Chou, Sung-Tau, et al.
Publicado: (2019)

Polyploids require Bik1 for kinetochore–microtubule attachment
por: Lin, Haijiang, et al.
Publicado: (2001)

Downregulation of microRNA-132 by DNA hypermethylation is associated with cell invasion in colorectal cancer
por: Qin, Jun, et al.
Publicado: (2015)

Salivary Exosomal MicroRNA-486-5p and MicroRNA-10b-5p in Oral and Oropharyngeal Squamous Cell Carcinoma
por: Faur, Cosmin Ioan, et al.
Publicado: (2022)

Combination of lenalidomide with vitamin D3 induces apoptosis in mantle cell lymphoma via demethylation of BIK
por: Brosseau, C, et al.
Publicado: (2014)

Muscle-enriched microRNA miR-486 decreases in circulation in response to exercise in young men
por: Aoi, Wataru, et al.
Publicado: (2013)

Overexpression of microRNA-486 affects the proliferation and chemosensitivity of mesothelioma cell lines by targeting PIM1
por: Pinelli, Silvana, et al.
Publicado: (2021)

[Retracted] MicroRNA‑383 suppresses cell proliferation and invasion in colorectal cancer by directly targeting paired box 6
por: Yan, Fei, et al.
Publicado: (2023)

BikDDA, a Mutant of Bik with Longer Half-Life Expression Protein, Can Be a Novel Therapeutic Gene for Triple-Negative Breast Cancer
por: Jiao, Shiping, et al.
Publicado: (2014)

Propofol Suppresses Proliferation, Migration, Invasion And Promotes Apoptosis By Upregulating microRNA-140-5p In Gastric Cancer Cells
por: Zhu, Fengbo, et al.
Publicado: (2019)

MicroRNA-362 Inhibits Cell Proliferation and Invasion by Directly Targeting SIX1 in Colorectal Cancer
por: Wan, Jin'e, et al.
Publicado: (2019)

MicroRNA-187 inhibits tumor growth and invasion by directly targeting CD276 in colorectal cancer
por: Wang, Zheng-Shi, et al.
Publicado: (2016)

[Retracted] MicroRNA‑212 inhibits colorectal cancer cell viability and invasion by directly targeting PIK3R3
por: Zhang, Jian, et al.
Publicado: (2023)

TGF-β induces apoptosis in human B cells via transcriptional regulation of BIK and BCL-X(L)
por: Spender, LC, et al.
Publicado: (2009)

BH3-only protein Bik is involved in both apoptosis induction and sensitivity to oxidative stress in multiple myeloma
por: Bodet, L, et al.
Publicado: (2010)

Neither loss of Bik alone, nor combined loss of Bik and Noxa, accelerate murine lymphoma development or render lymphoma cells resistant to DNA damaging drugs
por: Happo, L, et al.
Publicado: (2012)

Circular RNA circHUWE1 Is Upregulated and Promotes Cell Proliferation, Migration and Invasion in Colorectal Cancer by Sponging miR-486
por: Chen, Hong-Yu, et al.
Publicado: (2020)

MicroRNA-486 promotes a more catabolic phenotype in chondrocyte-like cells by targeting SIRT6: possible involvement in cartilage degradation in osteoarthritis
por: Yang, Jie, et al.
Publicado: (2021)

MicroRNA-744 Inhibits Cellular Proliferation and Invasion of Colorectal Cancer by Directly Targeting Oncogene Notch1
por: Shen, Jian, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_m84er0rdd1eoa2qb4im1buu5b7