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Role of Farnesoid X Receptor and Bile Acids in Hepatic Tumor Development
Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths worldwide, and an association between altered bile acid (BA) metabolism, down‐regulation of farnesoid X receptor (FXR), which is a master regulator of BA metabolism, and hepatocarcinogenesis has been documented. While global FXR defi...
Autores principales: | Takahashi, Shogo, Tanaka, Naoki, Fukami, Tatsuki, Xie, Cen, Yagai, Tomoki, Kim, Donghwan, Velenosi, Thomas J., Yan, Tingting, Krausz, Kristopher W., Levi, Moshe, Gonzalez, Frank J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287584/ https://www.ncbi.nlm.nih.gov/pubmed/30556042 http://dx.doi.org/10.1002/hep4.1263 |
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