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A Pathophysiologic Approach Combining Genetics and Insulin Resistance to Predict the Severity of Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is a complex disease dictated by both genetic and environmental factors. While insulin resistance (IR) is a key pathogenic driver, two common genetic variants in patatin‐like phospholipase domain containing 3 (PNPLA3) and transmembrane 6 superfamily member 2...
Autores principales: | Danford, Christopher J., Connelly, Margery A., Shalaurova, Irina, Kim, Misung, Herman, Mark A., Nasser, Imad, Otvos, James D., Afdhal, Nezam H., Jiang, Z. Gordon, Lai, Michelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287585/ https://www.ncbi.nlm.nih.gov/pubmed/30556036 http://dx.doi.org/10.1002/hep4.1267 |
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