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Alteration of the Retinoid Acid-CBP Signaling Pathway in Neural Crest Induction Contributes to Enteric Nervous System Disorder

Hirschsprung Disease (HSCR) and/or hypoganglionosis are common pediatric disorders that arise from developmental deficiencies of enteric neural crest cells (ENCCs). Retinoid acid (RA) signaling has been shown to affect neural crest (NC) development. However, the mechanisms underlying RA deficiency-i...

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Detalles Bibliográficos
Autores principales: Li, Cheng, Hu, Rong, Hou, Nali, Wang, Yi, Wang, Zhili, Yang, Ting, Gu, Yan, He, Mulan, Shi, Yu, Chen, Jie, Song, Weihong, Li, Tingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287626/
https://www.ncbi.nlm.nih.gov/pubmed/30560112
http://dx.doi.org/10.3389/fped.2018.00382