It’s Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia

Cancer stem-like cells (CSCs) are a subset of cancer cells that are resistant to conventional radiotherapy and chemotherapy. As such, CSCs have been recognized as playing a large role in tumor initiation and recurrence. Although hyperthermia is broadly used in cancer treatment either alone or in com...

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Detalles Bibliográficos
Autores principales: Huang, Haidong, Yu, Kevin, Mohammadi, Alireza, Karanthanasis, Efstathios, Godley, Andrew, Yu, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287629/
https://www.ncbi.nlm.nih.gov/pubmed/30542674
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author Huang, Haidong
Yu, Kevin
Mohammadi, Alireza
Karanthanasis, Efstathios
Godley, Andrew
Yu, Jennifer S.
author_facet Huang, Haidong
Yu, Kevin
Mohammadi, Alireza
Karanthanasis, Efstathios
Godley, Andrew
Yu, Jennifer S.
author_sort Huang, Haidong
collection PubMed
description Cancer stem-like cells (CSCs) are a subset of cancer cells that are resistant to conventional radiotherapy and chemotherapy. As such, CSCs have been recognized as playing a large role in tumor initiation and recurrence. Although hyperthermia is broadly used in cancer treatment either alone or in combination with radio- or chemo-therapy, its potential to target CSCs is not well understood. In this review, we discuss different types of hyperthermia and potential mechanisms of action in cancer treatment, particularly in regards to killing CSCs.
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spelling pubmed-62876292018-12-10 It’s Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia Huang, Haidong Yu, Kevin Mohammadi, Alireza Karanthanasis, Efstathios Godley, Andrew Yu, Jennifer S. J Stem Cell Transplant Biol Article Cancer stem-like cells (CSCs) are a subset of cancer cells that are resistant to conventional radiotherapy and chemotherapy. As such, CSCs have been recognized as playing a large role in tumor initiation and recurrence. Although hyperthermia is broadly used in cancer treatment either alone or in combination with radio- or chemo-therapy, its potential to target CSCs is not well understood. In this review, we discuss different types of hyperthermia and potential mechanisms of action in cancer treatment, particularly in regards to killing CSCs. 2017-12-29 2017 /pmc/articles/PMC6287629/ /pubmed/30542674 Text en This is an open access article distributed under the Creative Commons (http://creativecommons.org/licenses/by-nc-nd/4.0/) Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Huang, Haidong
Yu, Kevin
Mohammadi, Alireza
Karanthanasis, Efstathios
Godley, Andrew
Yu, Jennifer S.
It’s Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia
title It’s Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia
title_full It’s Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia
title_fullStr It’s Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia
title_full_unstemmed It’s Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia
title_short It’s Getting Hot in Here: Targeting Cancer Stem-like Cells with Hyperthermia
title_sort it’s getting hot in here: targeting cancer stem-like cells with hyperthermia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287629/
https://www.ncbi.nlm.nih.gov/pubmed/30542674
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