Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells

The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can function as in situ cancer vaccination by exposing tumor antigens and providing adjuvants for anti-tumor immune priming. In this regard, the mode of tumor cell death and the repertoire of released dam...

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Detalles Bibliográficos
Autores principales: Krombach, Julia, Hennel, Roman, Brix, Nikko, Orth, Michael, Schoetz, Ulrike, Ernst, Anne, Schuster, Jessica, Zuchtriegel, Gabriele, Reichel, Christoph A., Bierschenk, Susanne, Sperandio, Markus, Vogl, Thomas, Unkel, Steffen, Belka, Claus, Lauber, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287777/
https://www.ncbi.nlm.nih.gov/pubmed/30546963
http://dx.doi.org/10.1080/2162402X.2018.1523097

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