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Warming up the tumor microenvironment in order to enhance immunogenicity

We have recently demonstrated that intratumoral CpG-B vaccination enhances anti-tumor immunity and tumor regression in mice. We further show that the local delivery of TLR9 agonists converts the tolerogenic tumor microenvironment into an immunopermissive one, which may benefit current immunotherapeu...

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Detalles Bibliográficos
Autores principales: Humbert, Marion, Hugues, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287788/
https://www.ncbi.nlm.nih.gov/pubmed/30546946
http://dx.doi.org/10.1080/2162402X.2018.1510710