Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials

Multiple immunotherapeutics have been approved for cancer patients, however advanced solid tumors are frequently refractory to treatment. We evaluated the safety and immunogenicity of a vaccination approach with multimodal oncolytic potential in non-human primates (NHP) (Macaca fascicularis). Primat...

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Detalles Bibliográficos
Autores principales: Pol, Jonathan G., Acuna, Sergio A., Yadollahi, Beta, Tang, Nan, Stephenson, Kyle B., Atherton, Matthew J., Hanwell, David, El-Warrak, Alexander, Goldstein, Alyssa, Moloo, Badru, Turner, Patricia V., Lopez, Roberto, LaFrance, Sandra, Evelegh, Carole, Denisova, Galina, Parsons, Robin, Millar, Jamie, Stoll, Gautier, Martin, Chantal G., Pomoransky, Julia, Breitbach, Caroline J., Bramson, Jonathan L., Bell, John C., Wan, Yonghong, Stojdl, David F., Lichty, Brian D., McCart, J. Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287790/
https://www.ncbi.nlm.nih.gov/pubmed/30546947
http://dx.doi.org/10.1080/2162402X.2018.1512329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287790/
https://www.ncbi.nlm.nih.gov/pubmed/30546947
http://dx.doi.org/10.1080/2162402X.2018.1512329

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