Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells

In non-small cell lung carcinoma (NSCLC), stimulation of toll-like receptor 7 (TLR7), a receptor for single stranded RNA, is linked to tumor progression and resistance to anticancer chemotherapy. However, the mechanism of this effect has been elusive. Here, using a murine model of lung adenocarcinom...

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Detalles Bibliográficos
Autores principales: Dajon, Marion, Iribarren, Kristina, Petitprez, Florent, Marmier, Solenne, Lupo, Audrey, Gillard, Mélanie, Ouakrim, Hanane, Victor, Navas, Vincenzo, Di Bartolo, Joubert, Pierre Emmanuel, Kepp, Oliver, Kroemer, Guido, Alifano, Marco, Damotte, Diane, Cremer, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287801/
https://www.ncbi.nlm.nih.gov/pubmed/30546943
http://dx.doi.org/10.1080/2162402X.2018.1505174

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