Cargando…

Metabolomic investigations in cerebrospinal fluid of Parkinson's disease

The underlying mechanisms of Parkinson´s disease are not completely revealed. Especially, early diagnostic biomarkers are lacking. To characterize early pathophysiological events, research is focusing on metabolomics. In this case-control study we investigated the metabolic profile of 31 Parkinson´s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Willkommen, Desiree, Lucio, Marianna, Moritz, Franco, Forcisi, Sara, Kanawati, Basem, Smirnov, Kirill S., Schroeter, Michael, Sigaroudi, Ali, Schmitt-Kopplin, Philippe, Michalke, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287824/ https://www.ncbi.nlm.nih.gov/pubmed/30532185 http://dx.doi.org/10.1371/journal.pone.0208752

Ejemplares similares

Integrative Metabolomic and Metallomic Analysis in a Case–Control Cohort With Parkinson’s Disease
por: Lucio, Marianna, et al.
Publicado: (2019)

Interplay of Metallome and Metabolome in Amyotrophic Lateral Sclerosis: A Study on Cerebrospinal Fluid of Patients Carrying Disease-Related Gene Mutations
por: Solovyev, Nikolay, et al.
Publicado: (2023)

Iron Redox Speciation Analysis Using Capillary Electrophoresis Coupled to Inductively Coupled Plasma Mass Spectrometry (CE-ICP-MS)
por: Michalke, Bernhard, et al.
Publicado: (2019)

Changes in Brain Metallome/Metabolome Pattern due to a Single i.v. Injection of Manganese in Rats
por: Neth, Katharina, et al.
Publicado: (2015)

Oral versus intravenous iron replacement therapy distinctly alters the gut microbiota and metabolome in patients with IBD
por: Lee, Thomas, et al.
Publicado: (2017)

Pathway analysis of the transcriptome and metabolome of salt sensitive and tolerant poplar species reveals evolutionary adaption of stress tolerance mechanisms
por: Janz, Dennis, et al.
Publicado: (2010)

Usage of FT-ICR-MS Metabolomics for Characterizing the Chemical Signatures of Barrel-Aged Whisky
por: Roullier-Gall, Chloé, et al.
Publicado: (2018)

MetICA: independent component analysis for high-resolution mass-spectrometry based non-targeted metabolomics
por: Liu, Youzhong, et al.
Publicado: (2016)

Integrated transcriptomics and metabolomics decipher differences in the resistance of pedunculate oak to the herbivore Tortrix viridana L.
por: Kersten, Birgit, et al.
Publicado: (2013)

Relationships between drought, heat and air humidity responses revealed by transcriptome-metabolome co-analysis
por: Georgii, Elisabeth, et al.
Publicado: (2017)

Cerebrospinal Fluid Metabolome in Parkinson’s Disease and Multiple System Atrophy
por: Kwon, Do Hyeon, et al.
Publicado: (2022)

Previously unknown class of metalorganic compounds revealed in meteorites
por: Ruf, Alexander, et al.
Publicado: (2017)

Blue‐green fluorescence during hypersensitive cell death arises from phenylpropanoid deydrodimers
por: Kanawati, Basem, et al.
Publicado: (2023)

Novel Extraction Method for Combined Lipid and Metal Speciation From Caenorhabditis elegans With Focus on Iron Redox Status and Lipid Profiling
por: Blume, Bastian, et al.
Publicado: (2021)

Mining for Active Molecules in Probiotic Supernatant by Combining Non-Targeted Metabolomics and Immunoregulation Testing
por: Fonseca, Juliano Roldan, et al.
Publicado: (2022)

Data processing for fennel protein characterization by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS)
por: Melfi, Maria Teresa, et al.
Publicado: (2021)

Metabolic Fingerprint of PS3-Induced Resistance of Grapevine Leaves against Plasmopara viticola Revealed Differences in Elicitor-Triggered Defenses
por: Adrian, Marielle, et al.
Publicado: (2017)

The Metabolomic Approach Reveals the Alteration in Human Serum and Cerebrospinal Fluid Composition in Parkinson’s Disease Patients
por: Plewa, Szymon, et al.
Publicado: (2021)

Predictive Modeling of Alzheimer’s and Parkinson’s Disease Using Metabolomic and Lipidomic Profiles from Cerebrospinal Fluid
por: Hwangbo, Nathan, et al.
Publicado: (2022)

Selenium Species in Cerebrospinal Fluid and Hippocampal Volume among Individuals with Mild Cognitive Impairment
por: Vinceti, Marco, et al.
Publicado: (2022)

High Metabolomic Microdiversity within Co-Occurring Isolates of the Extremely Halophilic Bacterium Salinibacter ruber
por: Antón, Josefa, et al.
Publicado: (2013)

Metabolomics Reveals Metabolic Biomarkers of Crohn's Disease
por: Jansson, Janet, et al.
Publicado: (2009)

Digging into the low molecular weight peptidome with the OligoNet web server
por: Liu, Youzhong, et al.
Publicado: (2017)

Time Course of Metabolomic Alterations in Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage
por: Ho, Wing Mann, et al.
Publicado: (2020)

Disease-Related Changes in the Cerebrospinal Fluid Metabolome in Amyotrophic Lateral Sclerosis Detected by GC/TOFMS
por: Wuolikainen, Anna, et al.
Publicado: (2011)

Ceruloplasmin functional changes in Parkinson’s disease-cerebrospinal fluid
por: Barbariga, Marco, et al.
Publicado: (2015)

Longitudinal Measurements of Cerebrospinal Fluid Biomarkers in Parkinson's Disease
por: Hall, Sara, et al.
Publicado: (2016)

Blood and Cerebrospinal Fluid Biomarkers of Inflammation in Parkinson’s Disease
por: Zimmermann, Milan, et al.
Publicado: (2022)

The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis
por: Gray, Elizabeth, et al.
Publicado: (2015)

A selenium species in cerebrospinal fluid predicts conversion to Alzheimer’s dementia in persons with mild cognitive impairment
por: Vinceti, Marco, et al.
Publicado: (2017)

Doping Control Using High and Ultra-High Resolution Mass Spectrometry Based Non-Targeted Metabolomics-A Case Study of Salbutamol and Budesonide Abuse
por: Kiss, Agneta, et al.
Publicado: (2013)

Profiling Inflammatory Extracellular Vesicles in Plasma and Cerebrospinal Fluid: An Optimized Diagnostic Model for Parkinson’s Disease
por: Vacchi, Elena, et al.
Publicado: (2021)

Cerebrospinal fluid levels of proenkephalin and prodynorphin are differentially altered in Huntington’s and Parkinson’s disease
por: Barschke, Peggy, et al.
Publicado: (2022)

Regulatory role of hexosamine biosynthetic pathway on hepatic cancer stem cell marker CD133 under low glucose conditions
por: Lin, Shu-Hai, et al.
Publicado: (2016)

Cerebrospinal Fluid Lysosomal Enzymes and Alpha-Synuclein in Parkinson's Disease
por: Parnetti, Lucilla, et al.
Publicado: (2014)

Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease
por: Schröder, Jens B., et al.
Publicado: (2018)

Cerebrospinal fluid proteomics implicates the granin family in Parkinson’s disease
por: Rotunno, Melissa S., et al.
Publicado: (2020)

Cerebrospinal Fluid Cytokines and Neurodegeneration‐Associated Proteins in Parkinson's Disease
por: Wijeyekoon, Ruwani S., et al.
Publicado: (2020)

Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson’s disease
por: Lobanova, Evgeniia, et al.
Publicado: (2021)

Lipid Metabolism Disorder in Cerebrospinal Fluid Related to Parkinson’s Disease
por: Qiu, Jiewen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rqbtf91a6sq6vm7fmpfnetkfrl