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Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine

S-adenosylmethionine (SAM) is a donor which provides the methyl groups for histone or nucleic acid modification and phosphatidylcholine production. SAM is hypothesized to link metabolism and chromatin modification, however, its role in acute gene regulation is poorly understood. We recently found th...

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Detalles Bibliográficos
Autores principales: Ding, Wei, Higgins, Daniel P., Yadav, Dilip K., Godbole, Adwait A., Pukkila-Worley, Read, Walker, Amy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287882/
https://www.ncbi.nlm.nih.gov/pubmed/30485261
http://dx.doi.org/10.1371/journal.pgen.1007812