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Informing randomized clinical trials of respiratory syncytial virus vaccination during pregnancy to prevent recurrent childhood wheezing: A sample size analysis

BACKGROUND: Early RSV illness is associated with wheeze-associated disorders in childhood. Candidate respiratory syncytial virus (RSV) vaccines may prevent acute RSV illness in infants. We investigated the feasibility of maternal RSV vaccine trials to demonstrate reductions in recurrent childhood wh...

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Detalles Bibliográficos
Autores principales: Riddell, Corinne A., Bhat, Niranjan, Bont, Louis J., Dupont, William D., Feikin, Daniel R., Fell, Deshayne B., Gebretsadik, Tebeb, Hartert, Tina V., Hutcheon, Jennifer A., Karron, Ruth A., Nair, Harish, Reiner, Robert C., Shi, Ting, Sly, Peter D., Stein, Renato T., Wu, Pingsheng, Zar, Heather J., Ortiz, Justin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288067/
https://www.ncbi.nlm.nih.gov/pubmed/30473186
http://dx.doi.org/10.1016/j.vaccine.2018.10.041