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Assessing the feasibility of intranasal radiotracer administration for in brain PET imaging

INTRODUCTION: The development of clinically useful tracers for PET imaging is enormously challenging and expensive. The intranasal (IN) route of administration is purported to be a viable route for delivering drugs to the brain but has, as yet, not been investigated for the delivery of PET tracers....

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Detalles Bibliográficos
Autores principales: Singh, Nisha, Veronese, Mattia, O'Doherty, Jim, Sementa, Teresa, Bongarzone, Salvatore, Cash, Diana, Simmons, Camilla, Arcolin, Marco, Marsden, Paul K., Gee, Antony, Turkheimer, Federico E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288068/
https://www.ncbi.nlm.nih.gov/pubmed/30208358
http://dx.doi.org/10.1016/j.nucmedbio.2018.08.005