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FRET biosensor allows spatio-temporal observation of shear stress-induced polar RhoGDIα activation

Rho GDP-dissociation inhibitor α (RhoGDIα) is a known negative regulator of the Rho family that shuts off GDP/GTP cycling and cytoplasm/membrane translocation to regulate cell migration. However, to our knowledge, no reports are available that focus on how the RhoGDIα-Rho GTPases complex is activate...

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Detalles Bibliográficos
Autores principales:	Shao, Shuai, Liao, Xiaoling, Xie, Fei, Deng, Sha, Liu, Xue, Ristaniemi, Tapani, Liu, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288100/ https://www.ncbi.nlm.nih.gov/pubmed/30564745 http://dx.doi.org/10.1038/s42003-018-0232-2

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