Cargando…
Modeling genome-wide enzyme evolution predicts strong epistasis underlying catalytic turnover rates
Systems biology describes cellular phenotypes as properties that emerge from the complex interactions of individual system components. Little is known about how these interactions have affected the evolution of metabolic enzymes. Here, we combine genome-scale metabolic modeling with population genet...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288127/ https://www.ncbi.nlm.nih.gov/pubmed/30532008 http://dx.doi.org/10.1038/s41467-018-07649-1 |