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Bioluminescent reporter assay for monitoring ER stress in human beta cells

During type 1 diabetes development, cells in the islets of Langerhans engage adaptive mechanisms in response to inflammatory signals to cope with stress, to restore cellular homeostasis, and to preserve cell function. Disruption of these mechanisms may induce the formation of a repertoire of stress-...

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Detalles Bibliográficos
Autores principales: Kracht, Maria J. L., de Koning, Eelco J. P., Hoeben, Rob C., Roep, Bart O., Zaldumbide, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288136/
https://www.ncbi.nlm.nih.gov/pubmed/30532033
http://dx.doi.org/10.1038/s41598-018-36142-4