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Multi-experiment nonlinear mixed effect modeling of single-cell translation kinetics after transfection
Single-cell time-lapse studies have advanced the quantitative understanding of cellular pathways and their inherent cell-to-cell variability. However, parameters retrieved from individual experiments are model dependent and their estimation is limited, if based on solely one kind of experiment. Henc...
Autores principales: | Fröhlich, Fabian, Reiser, Anita, Fink, Laura, Woschée, Daniel, Ligon, Thomas, Theis, Fabian Joachim, Rädler, Joachim Oskar, Hasenauer, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288153/ https://www.ncbi.nlm.nih.gov/pubmed/30564456 http://dx.doi.org/10.1038/s41540-018-0079-7 |
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