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Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements
Caloric restriction (CR) stimulates development of functional beige fat and extends healthy lifespan. Here we show that compositional and functional changes in the gut microbiota contribute to a number of CR-induced metabolic improvements and promote fat browning. Mechanistically, these effects are...
Autores principales: | Fabbiano, Salvatore, Suárez-Zamorano, Nicolas, Chevalier, Claire, Lazarević, Vladimir, Kieser, Silas, Rigo, Dorothée, Leo, Stefano, Veyrat-Durebex, Christelle, Gaïa, Nadia, Maresca, Marcello, Merkler, Doron, Gomez de Agüero, Mercedes, Macpherson, Andrew, Schrenzel, Jacques, Trajkovski, Mirko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288182/ https://www.ncbi.nlm.nih.gov/pubmed/30174308 http://dx.doi.org/10.1016/j.cmet.2018.08.005 |
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