Development of an Infectious Cell Culture System for Hepatitis C Virus Genotype 6a Clinical Isolate Using a Novel Strategy and Its Sensitivity to Direct-Acting Antivirals

Hepatitis C virus (HCV) is classified into seven major genotypes, and genotype 6 is commonly prevalent in Asia, thus reverse genetic system representing genotype 6 isolates in prevalence is required. Here, we developed an infectious clone for a Chinese HCV 6a isolate (CH6a) using a novel strategy. W...

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Detalles Bibliográficos
Autores principales: Chen, Mingxiao, Zheng, Fuxiang, Yuan, Guosheng, Duan, Xiaobing, Rong, Liang, Liu, Junwei, Feng, Shengjun, Wang, Ziting, Wang, Min, Feng, Yetong, Zhou, Qing, Li, Jinqian, Deng, Kai, Li, Chunna, Xia, Jinyu, Rao, Guirong, Zhou, Yuanping, Fu, Yongshui, Li, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288186/
https://www.ncbi.nlm.nih.gov/pubmed/30564209
http://dx.doi.org/10.3389/fmicb.2018.02950

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