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Gasdermin E Does Not Limit Apoptotic Cell Disassembly by Promoting Early Onset of Secondary Necrosis in Jurkat T Cells and THP-1 Monocytes
During the progression of necroptosis and pyroptosis, the plasma membrane will become permeabilized through the activation of mixed lineage kinase domain like pseudokinase (MLKL) or gasdermin D (GSDMD), respectively. Recently, the progression of apoptotic cells into secondary necrotic cells followin...
Autores principales: | Tixeira, Rochelle, Shi, Bo, Parkes, Michael A. F., Hodge, Amy L., Caruso, Sarah, Hulett, Mark D., Baxter, Amy A., Phan, Thanh Kha, Poon, Ivan K. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288192/ https://www.ncbi.nlm.nih.gov/pubmed/30564238 http://dx.doi.org/10.3389/fimmu.2018.02842 |
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