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Bioactivity of Thyroid Hormone Analogs at Cancer Cells

In the context of genomic thyroid hormone actions in normal (noncancer) cells that involve primary interactions with nuclear thyroid hormone receptors (TRs), L-thyroxine (T4), and 3,3′,5′-triiodo-L-thyronine (reverse T3, rT3) have little bioactivity. In terms of TRs, T4 is a prohormone from which th...

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Detalles Bibliográficos
Autores principales:	Davis, Paul J., Tang, Heng-Yuan, Hercbergs, Aleck, Lin, Hung-Yun, Keating, Kelly A., Mousa, Shaker A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288194/ https://www.ncbi.nlm.nih.gov/pubmed/30564196 http://dx.doi.org/10.3389/fendo.2018.00739

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