Cargando…
DiDang Tang Inhibits Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Oxygen Glucose Deprivation and Intracerebral Hemorrhage Through Blockade of the GRP78-IRE1/PERK Pathways
DiDang Tang (DDT), a Chinese traditional medicine formula, contains 4 Chinese traditional medicine substances, has been widely used to treat intracerebral hemorrhage (ICH) patients. However, the molecular mechanisms of DDT for protecting neurons from oxygen and glucose deprivation (OGD)-induced endo...
Autores principales: | Huang, Qingxia, Lan, Tianye, Lu, Jing, Zhang, He, Zhang, Dongmei, Lou, Tingting, Xu, Peng, Ren, Jixiang, Zhao, Daqing, Sun, Liwei, Li, Xiangyan, Wang, Jian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288198/ https://www.ncbi.nlm.nih.gov/pubmed/30564125 http://dx.doi.org/10.3389/fphar.2018.01423 |
Ejemplares similares
-
The Protective Effect of DiDang Tang Against AlCl(3)-Induced Oxidative Stress and Apoptosis in PC12 Cells Through the Activation of SIRT1-Mediated Akt/Nrf2/HO-1 Pathway
por: Lu, Jing, et al.
Publicado: (2020) -
Didang Tang inhibits intracerebral hemorrhage-induced neuronal injury via ASK1/MKK7/JNK signaling pathway, network pharmacology-based analyses combined with experimental validation
por: Lu, Jing, et al.
Publicado: (2022) -
EGFR confers radioresistance in human oropharyngeal carcinoma by activating endoplasmic reticulum stress signaling PERK‐eIF2α‐GRP94 and IRE1α‐XBP1‐GRP78
por: Zhang, Miao, et al.
Publicado: (2018) -
The interaction between SPARC and GRP78 interferes with ER stress signaling and potentiates apoptosis via PERK/eIF2α and IRE1α/XBP-1 in colorectal cancer
por: Chern, Yi-Jye, et al.
Publicado: (2019) -
Porcine Circovirus 2 Deploys PERK Pathway and GRP78 for Its Enhanced Replication in PK-15 Cells
por: Zhou, Yingshan, et al.
Publicado: (2016)