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Extensive Alternative Splicing of KIR Transcripts
The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules. The complexity of the KIR cluster is reflected by, for instance, abundant levels of allelic polymorphism, gene copy number variation, and stochasti...
Autores principales: | Bruijnesteijn, Jesse, van der Wiel, Marit K. H., de Groot, Nanine, Otting, Nel, de Vos-Rouweler, Annemiek J. M., Lardy, Neubury M., de Groot, Natasja G., Bontrop, Ronald E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288254/ https://www.ncbi.nlm.nih.gov/pubmed/30564240 http://dx.doi.org/10.3389/fimmu.2018.02846 |
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