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Structure-Based Classification Defines the Discrete Conformational Classes Adopted by the Arenaviral GP1

The emergence of Old and New World arenaviruses from rodent reservoirs persistently threatens human health. The GP1 subunit of the envelope-displayed arenaviral glycoprotein spike complex (GPC) mediates host cell recognition and is an important determinant of cross-species transmission. Previous str...

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Detalles Bibliográficos
Autores principales: Pryce, Rhys, Ng, Weng M., Zeltina, Antra, Watanabe, Yasunori, El Omari, Kamel, Wagner, Armin, Bowden, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288339/
https://www.ncbi.nlm.nih.gov/pubmed/30305351
http://dx.doi.org/10.1128/JVI.01048-18