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Naturally Occurring Single Mutations in Ebola Virus Observably Impact Infectivity

Sequencing of Ebola virus (EBOV) genomes during the 2014–2016 epidemic identified several naturally occurring, dominant mutations potentially impacting virulence or tropism. In this study, we characterized EBOV variants carrying one of the following substitutions: A82V in the glycoprotein (GP), R111...

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Detalles Bibliográficos
Autores principales: Wong, Gary, He, Shihua, Leung, Anders, Cao, Wenguang, Bi, Yuhai, Zhang, Zirui, Zhu, Wenjun, Wang, Liang, Zhao, Yuhui, Cheng, Keding, Liu, Di, Liu, Wenjun, Kobasa, Darwyn, Gao, George F., Qiu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288345/
https://www.ncbi.nlm.nih.gov/pubmed/30333174
http://dx.doi.org/10.1128/JVI.01098-18