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A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions

The JAK2/STAT signaling pathway mediates cytokine receptor signals that are involved in cell growth, survival and homeostasis. JAK2 is a member of the Janus kinase (JAK) family and aberrant JAK2/STAT is involved with various diseases, making the pathway a therapeutic target. The similarity between t...

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Detalles Bibliográficos
Autores principales:	Lin, Tony Eight, HuangFu, Wei-Chun, Chao, Min-Wu, Sung, Tzu-Ying, Chang, Chao-Di, Chen, Yi-Ying, Hsieh, Jui-Hua, Tu, Huang-Ju, Huang, Han-Li, Pan, Shiow-Lin, Hsu, Kai-Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288363/ https://www.ncbi.nlm.nih.gov/pubmed/30564118 http://dx.doi.org/10.3389/fphar.2018.01379

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