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Transcriptional response to Wnt activation regulates the regenerative capacity of the mammalian cochlea

Lack of sensory hair cell (HC) regeneration in mammalian adults is a major contributor to hearing loss. In contrast, the neonatal mouse cochlea retains a transient capacity for regeneration, and forced Wnt activation in neonatal stages promotes supporting cell (SC) proliferation and induction of ect...

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Detalles Bibliográficos
Autores principales:	Samarajeewa, Anshula, Lenz, Danielle R., Xie, Lihong, Chiang, Hao, Kirchner, Rory, Mulvaney, Joanna F., Edge, Albert S. B., Dabdoub, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2018
Materias:	Stem Cells and Regeneration
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288390/ https://www.ncbi.nlm.nih.gov/pubmed/30389848 http://dx.doi.org/10.1242/dev.166579

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