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A New Tool for Complement Research: In vitro Reconstituted Human Classical Complement Pathway

The complement, as part of the innate immune system, represents the first line of defense against Gram-negative bacteria invading the bloodstream. The complement system is a zymogen cascade that ultimately assemble into the so-called membrane attack complex (MAC), which lyses Gram-negative bacteria...

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Detalles Bibliográficos
Autores principales: Mutti, Michele, Ramoni, Katharina, Nagy, Gábor, Nagy, Eszter, Szijártó, Valéria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288441/
https://www.ncbi.nlm.nih.gov/pubmed/30564230
http://dx.doi.org/10.3389/fimmu.2018.02770