Contribution of MUTYH Variants to Male Breast Cancer Risk: Results From a Multicenter Study in Italy

Inherited mutations in BRCA1, and, mainly, BRCA2 genes are associated with increased risk of male breast cancer (MBC). Mutations in PALB2 and CHEK2 genes may also increase MBC risk. Overall, these genes are functionally linked to DNA repair pathways, highlighting the central role of genome maintenan...

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Detalles Bibliográficos
Autores principales: Rizzolo, Piera, Silvestri, Valentina, Bucalo, Agostino, Zelli, Veronica, Valentini, Virginia, Catucci, Irene, Zanna, Ines, Masala, Giovanna, Bianchi, Simonetta, Spinelli, Alessandro Mauro, Tommasi, Stefania, Tibiletti, Maria Grazia, Russo, Antonio, Varesco, Liliana, Coppa, Anna, Calistri, Daniele, Cortesi, Laura, Viel, Alessandra, Bonanni, Bernardo, Azzollini, Jacopo, Manoukian, Siranoush, Montagna, Marco, Radice, Paolo, Palli, Domenico, Peterlongo, Paolo, Ottini, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288482/
https://www.ncbi.nlm.nih.gov/pubmed/30564557
http://dx.doi.org/10.3389/fonc.2018.00583

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