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Osteoporosis and Osteoporotic Fractures in Gastrointestinal Disease
Patients with gastrointestinal disease (GI) are at risk for osteopenia or osteoporosis, which can lead to fractures. Although these patients may be at risk from a young age, gastroenterologists often overlook this fact in practice. There are well-known GI diseases associated with osteopenia and oste...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Bone and Mineral Research
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288610/ https://www.ncbi.nlm.nih.gov/pubmed/30574465 http://dx.doi.org/10.11005/jbm.2018.25.4.213 |
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author | Oh, Hyun Jin Ryu, Kum Hei Park, Bum Joon Yoon, Byung-Ho |
author_facet | Oh, Hyun Jin Ryu, Kum Hei Park, Bum Joon Yoon, Byung-Ho |
author_sort | Oh, Hyun Jin |
collection | PubMed |
description | Patients with gastrointestinal disease (GI) are at risk for osteopenia or osteoporosis, which can lead to fractures. Although these patients may be at risk from a young age, gastroenterologists often overlook this fact in practice. There are well-known GI diseases associated with osteopenia and osteoporosis, such as the post-gastrectomy state, inflammatory bowel disease (IBD), and celiac disease. As there is an increase in the prevalence of IBD patients, newly diagnosed celiac disease in adulthood, and gastric cancer survivors following gastrectomy, bone disease in these patients becomes an important issue. Here, we have discussed osteoporosis and fractures in GI disease, especially in the post-gastrectomy state, IBD, and celiac disease. Although the pathogenesis of bone loss in each disease has not been fully identified, we have confirmed that the prevalence of osteoporosis and fractures in each of these diseases is high. There are scarce studies comparing the prevalence of osteoporosis or osteoporotic fractures in GI disease patients with studies in postmenopausal women, and specific guidelines for their management in each disease have not been established. Intensive surveillance and management are needed to ensure that these patients attain peak bone mass for age and sex to prevent fractures. |
format | Online Article Text |
id | pubmed-6288610 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Korean Society for Bone and Mineral Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-62886102018-12-20 Osteoporosis and Osteoporotic Fractures in Gastrointestinal Disease Oh, Hyun Jin Ryu, Kum Hei Park, Bum Joon Yoon, Byung-Ho J Bone Metab Review Article Patients with gastrointestinal disease (GI) are at risk for osteopenia or osteoporosis, which can lead to fractures. Although these patients may be at risk from a young age, gastroenterologists often overlook this fact in practice. There are well-known GI diseases associated with osteopenia and osteoporosis, such as the post-gastrectomy state, inflammatory bowel disease (IBD), and celiac disease. As there is an increase in the prevalence of IBD patients, newly diagnosed celiac disease in adulthood, and gastric cancer survivors following gastrectomy, bone disease in these patients becomes an important issue. Here, we have discussed osteoporosis and fractures in GI disease, especially in the post-gastrectomy state, IBD, and celiac disease. Although the pathogenesis of bone loss in each disease has not been fully identified, we have confirmed that the prevalence of osteoporosis and fractures in each of these diseases is high. There are scarce studies comparing the prevalence of osteoporosis or osteoporotic fractures in GI disease patients with studies in postmenopausal women, and specific guidelines for their management in each disease have not been established. Intensive surveillance and management are needed to ensure that these patients attain peak bone mass for age and sex to prevent fractures. The Korean Society for Bone and Mineral Research 2018-11 2018-11-30 /pmc/articles/PMC6288610/ /pubmed/30574465 http://dx.doi.org/10.11005/jbm.2018.25.4.213 Text en Copyright © 2018 The Korean Society for Bone and Mineral Research http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Oh, Hyun Jin Ryu, Kum Hei Park, Bum Joon Yoon, Byung-Ho Osteoporosis and Osteoporotic Fractures in Gastrointestinal Disease |
title | Osteoporosis and Osteoporotic Fractures in Gastrointestinal Disease |
title_full | Osteoporosis and Osteoporotic Fractures in Gastrointestinal Disease |
title_fullStr | Osteoporosis and Osteoporotic Fractures in Gastrointestinal Disease |
title_full_unstemmed | Osteoporosis and Osteoporotic Fractures in Gastrointestinal Disease |
title_short | Osteoporosis and Osteoporotic Fractures in Gastrointestinal Disease |
title_sort | osteoporosis and osteoporotic fractures in gastrointestinal disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288610/ https://www.ncbi.nlm.nih.gov/pubmed/30574465 http://dx.doi.org/10.11005/jbm.2018.25.4.213 |
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