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Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4

Programmed formation of DNA double-strand breaks (DSBs) initiates the meiotic homologous recombination pathway. This pathway is essential for proper chromosome segregation at the first meiotic division and fertility. Meiotic DSBs are catalyzed by Spo11. Several other proteins are essential for meiot...

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Detalles Bibliográficos
Autores principales:	Kumar, Rajeev, Oliver, Cecilia, Brun, Christine, Juarez-Martinez, Ariadna B, Tarabay, Yara, Kadlec, Jan, de Massy, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Life Science Alliance LLC 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288613/ https://www.ncbi.nlm.nih.gov/pubmed/30569039 http://dx.doi.org/10.26508/lsa.201800259

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