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Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study

AIM: To assess the incremental benefit of narrow band imaging (NBI) and white light endoscopy (WLE), randomizing the initial technique for the detection of residual neoplasia at the polypectomy scar after an endoscopic piecemeal mucosal resection (EPMR). METHODS: We conducted an observational study...

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Autores principales: Riu Pons, Fausto, Andreu, Montserrat, Gimeno Beltran, Javier, Álvarez-Gonzalez, Marco Antonio, Seoane Urgorri, Agustín, Dedeu, Josep Maria, Barranco Priego, Luis, Bessa, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288651/
https://www.ncbi.nlm.nih.gov/pubmed/30568394
http://dx.doi.org/10.3748/wjg.v24.i45.5179
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author Riu Pons, Fausto
Andreu, Montserrat
Gimeno Beltran, Javier
Álvarez-Gonzalez, Marco Antonio
Seoane Urgorri, Agustín
Dedeu, Josep Maria
Barranco Priego, Luis
Bessa, Xavier
author_facet Riu Pons, Fausto
Andreu, Montserrat
Gimeno Beltran, Javier
Álvarez-Gonzalez, Marco Antonio
Seoane Urgorri, Agustín
Dedeu, Josep Maria
Barranco Priego, Luis
Bessa, Xavier
author_sort Riu Pons, Fausto
collection PubMed
description AIM: To assess the incremental benefit of narrow band imaging (NBI) and white light endoscopy (WLE), randomizing the initial technique for the detection of residual neoplasia at the polypectomy scar after an endoscopic piecemeal mucosal resection (EPMR). METHODS: We conducted an observational study in an academic center to assess the incremental benefit of NBI and WLE randomly applied 1:1 (NBI-WLE or WLE-NBI) in the follow-up of a post-EPMR scar by the same endoscopist. RESULTS: A total of 112 EPMR scars were included. The median baseline polyp size was 20 mm (interquartile range: 14-30). At first review, NBI and WLE showed good sensitivity (85.0% vs 78.9%), specificity (77.1% vs 84.2%) and overall accuracy (80.0% vs 82.5%). NBI after WLE (WLE-NBI group) improved accuracy, but this difference was not statistically significant [area under the curve (AUC): 86.8% vs 81.6%, P = 0.15]. WLE after NBI (NBI-WLE group) did not improve accuracy (AUC: 81.4% vs 81.1%, P = 0.9). Overall, recurrence was found in 39/112 (34.8%) lesions. CONCLUSION: Although no statistically significant differences were found between the two techniques at the first post-EPMR assessment, the use of NBI after WLE may improve residual neoplasia detection. Nevertheless, biopsy is still required in the first scar review.
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spelling pubmed-62886512018-12-19 Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study Riu Pons, Fausto Andreu, Montserrat Gimeno Beltran, Javier Álvarez-Gonzalez, Marco Antonio Seoane Urgorri, Agustín Dedeu, Josep Maria Barranco Priego, Luis Bessa, Xavier World J Gastroenterol Observational Study AIM: To assess the incremental benefit of narrow band imaging (NBI) and white light endoscopy (WLE), randomizing the initial technique for the detection of residual neoplasia at the polypectomy scar after an endoscopic piecemeal mucosal resection (EPMR). METHODS: We conducted an observational study in an academic center to assess the incremental benefit of NBI and WLE randomly applied 1:1 (NBI-WLE or WLE-NBI) in the follow-up of a post-EPMR scar by the same endoscopist. RESULTS: A total of 112 EPMR scars were included. The median baseline polyp size was 20 mm (interquartile range: 14-30). At first review, NBI and WLE showed good sensitivity (85.0% vs 78.9%), specificity (77.1% vs 84.2%) and overall accuracy (80.0% vs 82.5%). NBI after WLE (WLE-NBI group) improved accuracy, but this difference was not statistically significant [area under the curve (AUC): 86.8% vs 81.6%, P = 0.15]. WLE after NBI (NBI-WLE group) did not improve accuracy (AUC: 81.4% vs 81.1%, P = 0.9). Overall, recurrence was found in 39/112 (34.8%) lesions. CONCLUSION: Although no statistically significant differences were found between the two techniques at the first post-EPMR assessment, the use of NBI after WLE may improve residual neoplasia detection. Nevertheless, biopsy is still required in the first scar review. Baishideng Publishing Group Inc 2018-12-07 2018-12-07 /pmc/articles/PMC6288651/ /pubmed/30568394 http://dx.doi.org/10.3748/wjg.v24.i45.5179 Text en ©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Observational Study
Riu Pons, Fausto
Andreu, Montserrat
Gimeno Beltran, Javier
Álvarez-Gonzalez, Marco Antonio
Seoane Urgorri, Agustín
Dedeu, Josep Maria
Barranco Priego, Luis
Bessa, Xavier
Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study
title Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study
title_full Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study
title_fullStr Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study
title_full_unstemmed Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study
title_short Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study
title_sort narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: a single-blind observational study
topic Observational Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288651/
https://www.ncbi.nlm.nih.gov/pubmed/30568394
http://dx.doi.org/10.3748/wjg.v24.i45.5179
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