Schistosoma mansoni antigen Sm-p80: prophylactic efficacy using TLR4 agonist vaccine adjuvant glucopyranosyl lipid A-Alum in murine and non-human primate models

Sm-p80, the large subunit of Schistosoma mansoni calpain, is a leading candidate for a schistosomiasis vaccine. The prophylactic and antifecundity efficacy of Sm-p80 has been tested in three animal models (mouse, hamster and baboon) using a multitude of vaccine formulations and approaches. In our co...

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Detalles Bibliográficos
Autores principales: Zhang, Weidong, Ahmad, Gul, Molehin, Adebayo J, Torben, Workineh, Le, Loc, Kim, Eunjee, Lazarus, Samra, Siddiqui, Arif J, Carter, Darrick, Siddiqui, Afzal A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288690/
https://www.ncbi.nlm.nih.gov/pubmed/29997146
http://dx.doi.org/10.1136/jim-2018-000786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288690/
https://www.ncbi.nlm.nih.gov/pubmed/29997146
http://dx.doi.org/10.1136/jim-2018-000786

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