Cargando…
Schistosoma mansoni antigen Sm-p80: prophylactic efficacy using TLR4 agonist vaccine adjuvant glucopyranosyl lipid A-Alum in murine and non-human primate models
Sm-p80, the large subunit of Schistosoma mansoni calpain, is a leading candidate for a schistosomiasis vaccine. The prophylactic and antifecundity efficacy of Sm-p80 has been tested in three animal models (mouse, hamster and baboon) using a multitude of vaccine formulations and approaches. In our co...
Autores principales: | Zhang, Weidong, Ahmad, Gul, Molehin, Adebayo J, Torben, Workineh, Le, Loc, Kim, Eunjee, Lazarus, Samra, Siddiqui, Arif J, Carter, Darrick, Siddiqui, Afzal A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288690/ https://www.ncbi.nlm.nih.gov/pubmed/29997146 http://dx.doi.org/10.1136/jim-2018-000786 |
Ejemplares similares
-
Fifteen Years of Sm-p80-Based Vaccine Trials in Nonhuman Primates: Antibodies From Vaccinated Baboons Confer Protection in vivo and in vitro From Schistosoma mansoni and Identification of Putative Correlative Markers of Protection
por: Zhang, Weidong, et al.
Publicado: (2020) -
Chronic whipworm infection exacerbates Schistosoma mansoni egg-induced hepatopathology in non-human primates
por: Le, Loc, et al.
Publicado: (2020) -
Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons
por: Rojo, Juan U., et al.
Publicado: (2017) -
Elucidation of Cellular Responses in Non-human Primates With Chronic Schistosomiasis Followed by Praziquantel Treatment
por: Melkus, Michael W., et al.
Publicado: (2020) -
Process Development of Sj-p80: A Low-Cost Transmission-Blocking Veterinary Vaccine for Asiatic Schistosomiasis
por: Molehin, Adebayo J., et al.
Publicado: (2021)