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Early use of donepezil against psychosis and cognitive decline in Parkinson’s disease: a randomised controlled trial for 2 years

OBJECTIVES: Brain acetylcholine is decreased even in patients with cognitively preserved Parkinson’s disease (PD). We investigated whether early and long-term use of donepezil prevents psychosis in non-demented PD patients. METHODS: A double-blinded, placebo-controlled trial was conducted. A total o...

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Detalles Bibliográficos
Autores principales:	Sawada, Hideyuki, Oeda, Tomoko, Kohsaka, Masayuki, Umemura, Atsushi, Tomita, Satoshi, Park, Kwiyoung, Mizoguchi, Kouichi, Matsuo, Hidenori, Hasegawa, Kazuko, Fujimura, Harutoshi, Sugiyama, Hiroshi, Nakamura, Michikazu, Kikuchi, Seishi, Yamamoto, Kenji, Fukuda, Toshiaki, Ito, Suminobu, Goto, Masashi, Kiyohara, Kosuke, Kawamura, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2018
Materias:	Neuropsychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288700/ https://www.ncbi.nlm.nih.gov/pubmed/30076270 http://dx.doi.org/10.1136/jnnp-2018-318107

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