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Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data
Up to half of all patients do not respond to pharmacological treatment as intended. A substantial fraction of these inter-individual differences is due to heritable factors and a growing number of associations between genetic variations and drug response phenotypes have been identified. Importantly,...
Autores principales: | Zhou, Yitian, Fujikura, Kohei, Mkrtchian, Souren, Lauschke, Volker M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288784/ https://www.ncbi.nlm.nih.gov/pubmed/30564131 http://dx.doi.org/10.3389/fphar.2018.01437 |
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