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Atomistic Model for Simulations of the Sedative Hypnotic Drug 2,2,2-Trichloroethanol

[Image: see text] 2,2,2-Trichloroethanol (TCE) is the active form of the sedative hypnotic drug chloral hydrate, one of the oldest sleep medications in the market. Understanding of TCE’s action mechanisms to its many targets, particularly within the ion channel family, could benefit from the state-o...

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Detalles Bibliográficos
Autores principales: Kiametis, Alessandra S., Stock, Letícia, Cirqueira, Leonardo, Treptow, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288786/
https://www.ncbi.nlm.nih.gov/pubmed/30556017
http://dx.doi.org/10.1021/acsomega.8b02017