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The Yeast DNA Damage Checkpoint Kinase Rad53 Targets the Exoribonuclease, Xrn1

The highly conserved DNA damage response (DDR) pathway monitors the genomic integrity of the cell and protects against genotoxic stresses. The apical kinases, Mec1 and Tel1 (ATR and ATM in human, respectively), initiate the DNA damage signaling cascade through the effector kinases, Rad53 and Chk1, t...

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Detalles Bibliográficos
Autores principales:	Lao, Jessica P., Ulrich, Katie M., Johnson, Jeffrey R., Newton, Billy W., Vashisht, Ajay A., Wohlschlegel, James A., Krogan, Nevan J., Toczyski, David P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2018
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288840/ https://www.ncbi.nlm.nih.gov/pubmed/30377154 http://dx.doi.org/10.1534/g3.118.200767

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