Tumor-derived exosomal HMGB1 fosters hepatocellular carcinoma immune evasion by promoting TIM-1(+) regulatory B cell expansion

BACKGROUND: Regulatory B (Breg) cells represent one of the B cell subsets that infiltrate solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, the phenotype, function and clinical relevance of Breg cells in human hepatocellular carcinoma (HCC) are presently unk...

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Detalles Bibliográficos
Autores principales: Ye, Linsen, Zhang, Qi, Cheng, Yusheng, Chen, Xiaolong, Wang, Guoying, Shi, Mengchen, Zhang, Tong, Cao, Yingjiao, Pan, Hang, Zhang, Liting, Wang, Genshu, Deng, Yinan, Yang, Yang, Chen, Guihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288912/
https://www.ncbi.nlm.nih.gov/pubmed/30526680
http://dx.doi.org/10.1186/s40425-018-0451-6

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