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Genome-wide DNA methylation profiling shows a distinct epigenetic signature associated with lung macrophages in cystic fibrosis

BACKGROUND: Lung macrophages are major participants in the pulmonary innate immune response. In the cystic fibrosis (CF) lung, the inability of lung macrophages to successfully regulate the exaggerated inflammatory response suggests dysfunctional innate immune cell function. In this study, we aim to...

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Detalles Bibliográficos
Autores principales:	Chen, Youdinghuan, Armstrong, David A., Salas, Lucas A., Hazlett, Haley F., Nymon, Amanda B., Dessaint, John A., Aridgides, Daniel S., Mellinger, Diane L., Liu, Xiaoying, Christensen, Brock C., Ashare, Alix
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288922/ https://www.ncbi.nlm.nih.gov/pubmed/30526669 http://dx.doi.org/10.1186/s13148-018-0580-2

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