The epithelial-to-mesenchymal transition induced by tumor-associated macrophages confers chemoresistance in peritoneally disseminated pancreatic cancer

BACKGROUND: The peritoneum is one of the most frequent metastatic sites in pancreatic cancer patients, and peritoneal dissemination makes this disease refractory due to aggressive progression and chemoresistance. Although the role of the tumor microenvironment in cancer development is recognized, th...

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Detalles Bibliográficos
Autores principales: Kuwada, Kazuya, Kagawa, Shunsuke, Yoshida, Ryuichi, Sakamoto, Shuichi, Ito, Atene, Watanabe, Megumi, Ieda, Takeshi, Kuroda, Shinji, Kikuchi, Satoru, Tazawa, Hiroshi, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288926/
https://www.ncbi.nlm.nih.gov/pubmed/30537992
http://dx.doi.org/10.1186/s13046-018-0981-2

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