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HDAC is indispensable for IFN-γ-induced B7-H1 expression in gastric cancer

BACKGROUND: B7 homolog 1 (B7-H1) overexpression on tumor cells is an important mechanism of immune evasion in gastric cancer (GC). Elucidation of the regulation of B7-H1 expression is urgently required to guide B7-H1-targeted cancer therapy. Interferon gamma (IFN-γ) is thought to be the main driving...

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Detalles Bibliográficos
Autores principales: Deng, Rui, Zhang, Peng, Liu, Weizhen, Zeng, Xiangyu, Ma, Xianxiong, Shi, Liang, Wang, Tao, Yin, Yuping, Chang, Weilong, Zhang, Pei, Wang, Guobin, Tao, Kaixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288935/
https://www.ncbi.nlm.nih.gov/pubmed/30537988
http://dx.doi.org/10.1186/s13148-018-0589-6