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Tuning Natural Killer Cell Anti-multiple Myeloma Reactivity by Targeting Inhibitory Signaling via KIR and NKG2A
Natural killer (NK) cells are attractive candidates for allogeneic cell-based immunotherapy due to their potent antitumor effector function and good safety profile. NK cells express killer immunoglobulin-like receptors (KIRs) and the NKG2A receptor important for NK cells education as well as providi...
Autores principales: | Mahaweni, Niken M., Ehlers, Femke A. I., Bos, Gerard M. J., Wieten, Lotte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288976/ https://www.ncbi.nlm.nih.gov/pubmed/30564241 http://dx.doi.org/10.3389/fimmu.2018.02848 |
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