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Attenuation of Tumor Suppressive Function of FBXO16 Ubiquitin Ligase Activates Wnt Signaling In Glioblastoma()

Glioblastoma (GBM) is one of the most aggressive and lethal types of brain tumor. Despite the advancements in conventional or targeted therapies, median survival of GBM patients is less than 12 months. Amongst various signaling pathways aberrantly activated in glioma, active Wnt/β-catenin signaling...

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Detalles Bibliográficos
Autores principales: Khan, Mohsina, Muzumdar, Dattatraya, Shiras, Anjali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288984/
https://www.ncbi.nlm.nih.gov/pubmed/30530053
http://dx.doi.org/10.1016/j.neo.2018.11.005